Here we considered designs consisting of a small number of spatially non-selective sub-pulses optimized over either a single 2D plane or 3D. Pulse design for saturation homogeneity (PUSH) optimizes pTx RF pulses by considering uniformity of root-mean squared B 1 +, B 1 rms, which relates to the rate of semisolid saturation. The semisolid magnetization is usually modeled as being purely longitudinal, with the applied B 1 + field saturating but not rotating its magnetization thus, standard pTx pulse design methods do not apply. This work proposes a novel RF pulse design for parallel transmit (pTx) systems to obtain uniform saturation of semisolid magnetization for magnetization transfer (MT) contrast in the presence of transmit field B 1 + inhomogeneities.
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